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Do not take Cialis if you: take any medicines called "nitrates". use recreational drugs called "poppers" like amyl nitrite and butyl nitrite. take any medicines called guanylate cyclase stimulators, such as riociguat.

are allergic to Cialis or Adcirca, or any order generic sildenafil of its ingredients.

Call your healthcare provider or get help right away if you have any of the symptoms of an allergic reaction listed above.

Do not take Viagra if you: take medicines called nitrates (such as nitroglycerin) use street drugs called "poppers" such as amyl nitrate or amyl nitrite, and butyl nitrate take any medicines called guanylate cyclase stimulators such as riociguat (Adempas) are allergic to sildenafil, as contained in Viagra and REVATIO, or any of the ingredients in Viagra. See the end of this leaflet for a complete list of ingredients in Viagra. Tell your healthcare provider about all the medicines you take1, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Viagra may affect the way other medicines work, and other medicines may affect the way Viagra works causing side effects. Especially tell your healthcare provider if you take any of the following: medicines called nitrates (see "What is the most important information I should know about Viagra?") medicines called guanylate cyclase stimulators, such as riociguat (Adempas) medicines called alpha blockers such as Hytrin (terazosin HCl), Flomax (tamsulosin HCl), Cardura (doxazosin mesylate), Minipress (prazosin HCl), Uroxatral (alfuzosin HCl), Jalyn (dutasteride and tamsulosin HCl), or Rapaflo (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients, the use of Viagra with alpha-blockers can lead to a drop in blood pressure or to fainting. medicines called HIVprotease inhibitors, such as ritonavir (Norvir), indinavir sulfate (Crixivan), saquinavir (Fortovase or Invirase) or atazanavir sulfate (Reyataz) some types of oralantifungal medicines, such as ketoconazole (Nizoral), and itraconazole (Sporanox) some types of antibiotics, such as clarithromycin (Biaxin), telithromycin (Ketek), or erythromycin other medicines that treat high blood pressure other medicines or treatments for ED. Viagra contains sildenafil, which is the same medicine found in another drug called REVATIO. REVATIO is used to treat a rare disease called pulmonary arterial hypertension (PAH).

Viagra should not be used with REVATIO or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such as Adcirca [tadalafil]). Ask your healthcare provider or pharmacist for a list of these medicines, if you are not sure. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

Take Cialis exactly as your healthcare provider prescribes it.

Your healthcare provider will prescribe the dose that is right for you. Some men can only take a low dose of Cialis or may have to take it less often, because of medical conditions or medicines they take.

Do not change your dose or the way you take Cialis without talking to your healthcare provider. Your healthcare provider may lower or raise your dose, depending on how your body reacts to Cialis and your health condition. If you take too much Cialis, call your healthcare provider or emergency room right away.

Take Viagra exactly as your healthcare provider tells you to take it. Your healthcare provider will tell you how much Viagra to take and when to take it. Your healthcare provider may change your dose if needed.

You may take Viagra between 30 minutes to 4 hours before sexual activity if needed.

If you take Viagra after a high fat meal (such as a cheeseburger and french fries), Viagra may take a little longer to start working. If you accidentally take too much Viagra, call your doctor or go to the nearest hospital emergency room right away.

Nitrates: Administration of VIAGRA to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form either regularly and/or intermittently, is contraindicated. VIAGRA was shown to potentiate the hypotensive effect of nitrates.

Concomitant Guanylate Cyclase (GC) Stimulators: Do not use VIAGRA in patients who are using a GC stimulator, such as riociguat. PDE5 inhibitors, including VIAGRA, may potentiate the hypotensive effects of GC stimulators.

Hypersensitivity Reactions: VIAGRA is contraindicated in patients with a known hypersensitivity to sildenafil, as contained in VIAGRA and REVATIO, or any component of the tablet.

Hypersensitivity reactions have been reported including rash and urticaria. Cardiovascular: Patients should not use VIAGRA if sexual activity is inadvisable due to cardiovascular status.

Physicians should carefully consider whether their patients with underlying cardiovascular disease could be affected adversely by the vasodilatory effects of VIAGRA, especially in combination with sexual activity. There are no controlled clinical data on the safety or efficacy of VIAGRA in patients with the following characteristics: recent serious cardiovascular events, hypotension, or uncontrolled hypertension; if prescribed, this should be done with caution.

Prolonged Erection: Prolonged erection greater than 4 hours and priapism (painful erections greater than 6 hours in duration) have been reported infrequently. In the event of an erection that persists longer than 4 hours, the patient should seek immediate medical assistance. If priapism is not treated immediately, penile tissue damage and permanent loss of potency could result. Use VIAGRA with caution in patients predisposed to priapism.

Effects on the Eye: Patients should stop VIAGRA and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). VIAGRA should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION.

There are no controlled clinical data on the safety or efficacy of VIAGRA in patients with retinitis pigmentosa; if prescribed, this should be done with caution. Hearing Loss: Sudden decrease or loss of hearing has been reported in temporal association with the intake of PDE5 inhibitors, including VIAGRA.

(It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors.) Physicians should advise patients to stop taking PDE5 inhibitors, including VIAGRA, and seek prompt medical attention in the event of sudden decrease or loss of hearing.

Potential Drug Interactions: VIAGRA can potentiate the hypotensive effects of nitrates, alpha-blockers, and antihypertensives. Initiate VIAGRA at 25 mg with concomitant use of alpha-blockers. CYP3A4 inhibitors (eg, ritonavir, ketoconazole, itraconazole, erythromycin) increase VIAGRA plasma exposure. Do not exceed 25 mg of VIAGRA in a 48-hour period with ritonavir. Consider a starting dose of 25 mg of VIAGRA with erythromycin or strong buy sildenafil reddit CYP3A4 inhibitors (eg, ketoconazole, itraconazole, saquinavir).

Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures. Specific Populations: Consider buy sildenafil 20 mg a starting dose of 25 mg of VIAGRA for patients age >65, patients with hepatic impairment, or severe renal impairment.

Sexually Transmitted Diseases: Use of VIAGRA offers no protection against sexually transmitted diseases, including the human immunodeficiency virus (HIV); therefore, physicians should consider counseling their patients about protective measures.

Adverse Reactions: The most common adverse reactions (?2%) with VIAGRA 25 mg, 50 mg, 100 mg vs placebo, respectively, include headache (16%, 21%, 28% vs 7%), flushing (10%, 19%, 18% vs 2%), dyspepsia (3%, 9%, 17% vs 2%), abnormal vision (1%, 2%, 11% vs 1%), nasal congestion (4%, 4%, 9% vs 2%), back pain (3%, 4%, 4% vs 2%), myalgia (2%, 2%, 4% vs 1%), nausea (2%, 3%, 3% vs 1%), dizziness (3%, 4%, 3% vs 2%), and rash (1%, 2%, 3% vs 1%).

VIAGRA ® (sildenafil citrate) is indicated for the treatment of erectile dysfunction (ED). By participating in the VIAGRA Savings Offer Program, you acknowledge that you currently meet the eligibility criteria and will comply with the terms and conditions described below: This Savings Offer is not valid for prescriptions that are reimbursed, in whole or in part, by Medicaid, Medicare, TRICARE, Veterans Affairs healthcare, or any other federal or state healthcare program (including any state prescription order generic sildenafil drug assistance program), or the Government Health Insurance Plan available in Puerto Rico (formerly known as "La Reforma de Salud") The value of this Savings Offer is limited to $350 per use or the amount of your co-pay, whichever is less This Savings Offer is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plans or other health or pharmacy benefit programs You must deduct the value received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf This Savings Offer is limited to 50% savings off the amount of your co-pay or your out-of-pocket cost, whichever is less, with a maximum savings of $350 off each prescription for up to 12 prescriptions in a calendar year. Total maximum savings for this Savings Offer are $4,200 You must be 18 years of age or older to redeem this Savings Offer Patients who are enrolled order generic sildenafil in Medicare, Medicaid, or another state or federal healthcare program may use this Savings Offer if paying for the prescription covered by this Savings Offer outside of their government insurance benefit, and no claim is submitted to Medicare, Medicaid, or any federal or state healthcare program. Such patients must not apply any out-of-pocket expenses incurred using this Savings Offer toward any government insurance benefit out-of-pocket spending calculations, such as Medicare Part D true out-of-pocket (TrOOP) costs You are responsible for reporting use of this Savings Offer to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using this Savings Offer, as may be required. You should not use this Savings Offer if your insurer or health plan prohibits use of manufacturer Savings Offers This Savings Offer is not valid for Massachusetts or California residents whose prescriptions are covered, in whole or in part, by third-party insurance This Savings Offer is not valid where prohibited by law This Savings Offer cannot be combined with any other rebate/offer, free trial, or similar offer for the specified prescription This Savings Offer will be accepted only at participating pharmacies This Savings Offer is not health insurance This Savings Offer is good only in the U.S.

and Puerto Rico This Savings Offer is limited to 1 per person during this offering period and is not transferable No other purchase is necessary This Savings Offer may not be redeemed more than once per 30 days per patient Data related to your redemption of this Savings Offer may be collected, analyzed, and order generic sildenafil shared with Pfizer for market research and other purposes related to assessing Pfizer's programs. Data shared with Pfizer will be aggregated and de-identified; it will be combined with data related to other Savings Offer redemptions and will not identify you Pfizer reserves the right to rescind, revoke, or amend this Savings Offer without notice No membership fees. The Savings Offer and Program expire on 12/31/2021 For further information, call 1-855-842-4722, visit VIAGRA.com , or write: Pfizer Inc., 235 E 42nd Street, New York, NY 10017. If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this Savings Offer.

Pay for your VIAGRA prescription and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: VIAGRA Savings Offer, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your VIAGRA Savings Card, your name, and mailing address.

Please expect up to 4 to 6 weeks for reimbursement.

Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. 1 Medical Affiliated Research Center, Huntsville, AL, USA.

2 Connecticut Clinical Research Center, Waterbury, CT, USA.

3 California Professional Research, Newport Beach, CA, USA. 5 Formerly Pfizer Global Research and Development, Sandwich, UK, currently PPD Inc, Cambridge, UK. 6 Members of the multicenter study group are listed in the appendix.

Because sildenafil citrate is a treatment, not a cure, for erectile dysfunction (ED), many men may choose to use it for an extended period. Men with ED who had previously completed 1 of 4 double-blind trials with short-term open-label extension (combined duration, 0.9–1.2 years) were eligible for this 4-year, open-label, extension study, which assessed the safety and effectiveness of flexible doses (25, 50, and 100 mg sildenafil) used as needed.



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