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Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy. Kloner, Morris Brown, L.Michael Prisant, Mike Collins, for the Sildenafil Study Group, Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy, American Journal of Hypertension , Volume 14, Issue 1, cvs price for sildenafil January 2001, Pages 70–73, https://doi.org/10.1016/S0895-7061(00)01177-8.

Oral sildenafil is an effective treatment for erectile dysfunction (ED), which is a common complaint for

patients

with hypertension and those taking antihypertensive agents. This post hoc subanalysis assessed the efficacy and safety of sildenafil in men with ED who were receiving concomitant antihypertensive medication.

Efficacy was assessed in 3414 men (1218 of whom were taking antihypertensive medication) who received sildenafil (5 to 200 mg) or placebo for 6 weeks to 6 months in 10 double-blind, placebo-controlled studies.

The significant improvements in erectile function demonstrated by sildenafil-treated patients were comparable in patients taking and those not taking antihypertensive medication.

Safety was assessed in 3975 men (1094 of whom were taking one or more antihypertensive agent, classified as a diuretic, ?-blocker, ? 1 -blocker, angiotensin converting enzyme inhibitor, or calcium channel blocker), who received sildenafil or placebo in 18 double-blind, placebo-controlled studies. For patients taking sildenafil and antihypertensive medication, the incidence of treatment-related adverse events (34%) was similar to that for sildenafil-treated patients not taking any antihypertensive agent (38%).

The incidences of the most common adverse events and of adverse events potentially related to blood pressure decreases (eg, hypotension, dizziness, and syncope) were similar in both sildenafil groups. The number of antihypertensive medications taken from among the five classes had no effect on the adverse event profile of sildenafil.

Sildenafil is an sildenafil tablet buy online effective and well-tolerated treatment for ED in patients taking concomitant antihypertensive medication, including those on multidrug regimens. Am J Hypertens 2001;14:70–73 © 2001 American Journal of Hypertension, Ltd. Erectile dysfunction (ED), the inability to achieve or maintain an erection sufficient for satisfactory sexual activity, 1 is a common problem in patients with hypertension and in those being treated with antihypertensive agents.



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