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Apos 2 meses, realizou-se controle clinico e biopsia gastrica para avaliar erradicacao do Helicobacter pylori. Resultados - Helicobacter pylori foi erradicado em 16/25 pacientes (64% - IC(95%) = 45-83%), em 11/15 (73% - IC(95%) - 51-95%) que utilizaram esquema antimicrobiano por 10 dias e em 5/10 (50% - IC(95%) = 19-81%) que utilizaram o esquema por 7 dias. Houve boa aceitacao do tratamento antimicrobiano e efeitos colaterais ocorreram em dois pacientes (8%).

Conclusoes - O indice de erradicacao obtido (64%) foi de eficacia moderada.

Os dados da presente serie sugerem que o esquema antimicrobiano por 10 dias (73%) seja mais eficaz que o esquema por 7 dias (50%) para tratamento da infeccao por Helicobacter pylori em nossa populacao, embora seja necessaria amostragem maior. Bamford KB, Bickley J,

Collins

JS, Johnston BJ, Pott S, Boston V, Owen RJ, Sloan JM.

Helicobacter pylori comparison of DNA fingerprints

provides

evidence for intrafamilial infection. Banatvala N, Davies GR, Abdi Y, Clements L, Rampton DS, Hardie JM, Feldman RA.

High prevalence of Helicobacter pylori metronidazole resistance in migrants to east London: relation with previous nitromidazole exposure and gastroduodenal disease. Barabino A, Dufour C, Marino CE, Claudiani F, Alessandri AD. Unexplained refractory iron deficiency anemia associated with Helicobacter pylori gastric infection in children: further clinical evidence.

Helicobacter pylori and peptic disease in pediatric patient.

Effective 2-wk therapy for Helicobacter pylori disease in children. Helicobacter pylori infection in children: a consensus statement.

Current European concepts in the management of Helicobacter pylori . Fiedoreck SC, Casteel HB, Pumphrey CL, Evans DJ Jr, Evans DG, Klein PD, Graham DY.

The role of Helicobacter pylori in recurrent, functional abdominal pain in children.

Treatment and long-term follow-up of Helicobacter pylori associated duodenal ulcer disease in children. Is Helicobacter pylori associated with non-ulcer dyspepsia and will eradication improve symptoms?

Managing intrafamilial dissemination of Helicobacter pylori gastric infection improves eradication rates in children [letter]. Omeprazole-based dual and triple regimens for Helicobacter pylori eradication in children. In: Farhat CK, Carvalho ES, Carvalho LHFR, Succi RCM, editores. Gastrite primaria associada ao Helicobacter pylori em criancas. Kiyota K, Habu Y, Sugano Y, Inokuchi H, Mizuno S, Kimoto K, Kawai K. Comparison of 1-week and 2-week triple therapy with omeprazole, amoxycillin, and clarithromycin in peptic ulcer patients with Helicobacter pylori infection: results of a randomized controlled trial. Iron-deficiency anemia associated with Helicobacter pylori gastritis.

Helicobacter pylori infection and childhood recurrent abdominal pain: lack of evidence for a cause and effect relationship.

Miyaji H, Azuma T, Ito S, Suto H, Ito Y, Yamazaki Y, Sato F, Hirai M, Kuriyama M, Kato T, Kohli Y.

Susceptibility of Helicobacter pylori isolates to metronidazole, clarithromycin and amoxycillin in vitro and in clinical treatment in Japan. Oderda G, Ponzetto A, Boero M, Bellis D, Forni M, Vaira D, amoxicillin & clavulanic acid Ansaldi N. Family treatment of symptomatic children with Helicobacter pylori infection. Management of

Helicobacter

pylori infection in children. Avaliacao de esquema triplice contendo claritromicina, citrato de bismuto coloidal e derivados nitroimidazolicos no tratamento de erradicacao do Helicobacter pylori .

In: IX Congresso Brasileiro de amoxicillin prescribing information Gastroenterologia Pediatrica, Natal, 1998. Patchett S, Beattie S, Leen E, Keane C, O'Morain C. Eradicating Helicobacter pylori and symptoms of non-ulcer dyspepsia.

Pilotto A, Leandro G, Franceschi M, Rassu M, Bozzola L, Furlan F, Di Mario F, Valerio G. The effect of antibiotic resistance on the outcome of three 1-week triple

therapies

against Helicobacter pylori .

Queiroz DMM, Coimbra RS, Mendes EN,

Rocha

GA, Alves VML, Oliveira CA, Lima Jr GF.

Metronidazole-resistant Helicobacter pylori in a developing country. Cure of duodenal ulcer associated with eradication of Helicobacter pylori . How should Helicobacter pylori infected children be managed? Rowland M, Kumar D, Daly L, O'Connor P, Vaughan D, Drumm B.

Low rates of Helicobacter pylori reinfection in children. Sherman P, Hassai E, Hunt RH, Fallone CA, Veldhuyzen van Zanten, Thomson ABR. Canadian Helicobacter Study Group Consensus Conference on the approach to Helicobacter pylori infection in children and adolescents. Helicobacter pylori gastritis in children: efficacy of 2 weeks of treatment with clarithromycin, amoxicillin and omeprazole. Clarithromycin resistance in Helicobacter pylori : prevalence in untreated dyspeptic patients and stability in vitro.

Division of Pediatric Gastroenterology, Federal University of Sao Paulo - "Escola Paulista de Medicina" - UNIFESP-EPM, Sao Paulo, SP, Brazil. * Assistant Professor, Division of Pediatric Gastroenterology, UNIFESP-EPM.

** Postgraduate student, Division of Pediatric Gastroenterology, UNIFESP-EPM.

*** Assistant Professor, Division of Pediatric Gastroenterology - Faculdade de Medicina da Santa Casa de Sao Paulo.

**** Assistant Professor, Department of Medical Pathology, UNIFESP-EPM.

Elisabete Kawakami - Rua Pedro de Toledo, 441 - Vila Clementino - 04039-031 - Sao Paulo - SP - Brazil.

All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Seng, 320 01331-020 amoxicillin 300 mg Sao Paulo - SP Brasil Tel./Fax: +55 11 3147-6227.

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