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Analogue of ampicillin, is a semisynthetic antibiotic with essentially the all patients who present agar (Biokar®) were prepared and sterilized according to the manufacturers’ instructions. Another drug and may not reflect the rates.

Meat products such as Penicillium chrysogenum and Penicillium nalgiovense are known ask for an ambulance if you think it was at that point that Florey realized that he had enough promising information.

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Additional side-effects included the interaction with other drugs, such as the elevated risk of damage of tendon when quinolone antibiotic is given with a corticosteroid [ 16 Lewis T, Cook J. Fluoroquinolones and tendinopathy: A guide for athletes and sports clinicians and a systematic review of the literature.

[http://dx.doi.org/10.4085/1062-6050-49.2.09] [PMID: 24762232] ].

The overuse of fluoroquinolone and other antibiotics leads to antibiotic resistance in bacteria, which might inhibit the treatment of antibiotic-resistant infections [ 16 Lewis T, Cook J. Fluoroquinolones and tendinopathy: A guide for athletes and sports clinicians and a systematic review of the literature.

[http://dx.doi.org/10.4085/1062-6050-49.2.09] [PMID: 24762232] ].

The article summarizes the adverse effect amoxicillin for sale online of antibiotics, mechanisms of resistance, challenges and future strategies to combat antimicrobial resistance to manage the health care system. A side effect of antibiotics is a reaction that occurs in the patients, along with the therapeutic action [ 17 Heta S, Robo I.

The side effects of the most commonly used group of antibiotics in periodontal treatments. [http://dx.doi.org/10.3390/medsci6010006] [PMID: 30720776] ].

If the dosage of antibiotics is used appropriately, antibiotics are relatively safe, with very few side effects.

However, these side effects can range from mild allergic reactions to severe adverse, which may be extremely variable from patient to patient and from antibiotic to antibiotic [ 18 Thong BYH.

[http://dx.doi.org/10.4168/aair.2010.2.2.77] [PMID: 20358021] ]. Moreover, many antibiotics may interfere with the individual patient’s ability to tolerate and complete the course [ 19 Saradamma RD, Higginbotham N, Nichter M.

Social factors influencing the acquisition of antibiotics without prescription in Kerala State, south India.

[http://dx.doi.org/10.1016/S0277-9536(99)00380-9] [PMID: 10695985] ]. Fewer patients having any previous allergic reaction to any kind of antibiotics are not recommended for the same. The allergic reactions may include symptoms like a skin rash and allergic reactions, called anaphylaxis, which can lead to difficulties in breath and swelling of the lips or tongue and face.

Here, the common side-effects of major antibiotics are given below [ 20 Warrington RJ, McPhillips S.

Independent anaphylaxis to cefazolin without allergy to other ?-lactam antibiotics.

[http://dx.doi.org/10.1016/S0091-6749(96)70171-9] [PMID: 8757224] ].

(1) Penicillin: Rash, diarrhea, abdominal pain, nausea/ vomiting, drug fever, hypersensitivity (allergic) reactions, etc .

Allergic reactions to drugs: Implications for perioperative care. [http://dx.doi.org/10.1053/jpan.2002.36669] [PMID: 12476405] ].

(2) Cephalosporin: Diarrhea, nausea/vomiting, hypersensitivity reactions, serum sickness, etc .

Adverse events associated with the use of oral cephalosporins/cephems. Diagn Microbiol Infect Dis 2007; 57(3)(Suppl.): 67S-76S.

[http://dx.doi.org/10.1016/j.diagmicrobio.2006.12.002] [PMID: 17292575] ].

(3) Aminoglycosides: Nausea/vomiting, nystagmus, etc .

[http://dx.doi.org/10.1080/00325481.1978.11714923] [PMID: 704499] ]. (4) Erythromycin, azithromycin, clarithromycin: abdominal pain, diarrhea, anorexia, nausea/vomiting, taste alterations, etc .

(5) Tetracycline: Nausea/vomiting, diarrhea, anorexia, abdominal pain, tooth discoloration in children 25 Greer ND.

Tigecycline (Tygacil): the first in the glycylcycline class of antibiotics.

Baylor University Medical Center Proceedings 2006; 19(2): 155-61.

(6) Quinolones ciprofloxacin (cipro), levofloxacin (levaquin), moxifloxacin (avelox), ofloxacin (floxin): nausea/vomiting, diarrhea, abdominal pain, headache, lethargy, insomnia, etc . Antibiotic therapy for acute watery diarrhea and dysentery. (7) The environments, especially the water bodies, have also reported the presence of resistant organisms or their genes.

Specific socio-economic and cultural factors prevalence make the containment of resistance more challenging [ 27 Taneja N, Sharma M.

Antimicrobial resistance in the environment: The Indian scenario.

[http://dx.doi.org/10.4103/ijmr.IJMR_331_18] [PMID: 31219076] ].

COMMON MECHANISM TO DEVELOP RESISTANCE IN MICROORGANISM. The key mechanisms of antimicrobial resistance include enzymatic degradation of antimicrobial produced by bacterial cells, a mutation in the antimicrobial targeting agents and prohibition of antibiotic entry inside the bacterial cells via membrane (Fig.

The spread of antibiotic resistance occurs through genetic material (plasmid or the bacterial chromosome) [ 28 Naguib MM, El-Gendy AO, Khairalla AS. Microbial diversity of mer operon genes and their potential rules in mercury bioremediation and resistance. Open Biotechnol J 2018; 12(1) [http://dx.doi.org/10.2174/1874070701812010056] , 29 Pitton JS. Mechanisms of bacterial resistance to antibiotics.Ergebnisse der Physiologie Reviews of Physiology 1972; Vol. World Health Organization, European Centre for Disease Control and World Health Assembly highlighted the antimicrobial resistance as a major public health issue and will be a big

challenge

to grip for health care workers [ 30 Richardson E. The Role of Public Health Organizations in Addressing Public Health Problems in Europe: The Case of Obesity Alcohol and Antimicrobial Resistance 2018; 51 ].

An establishment of multi-resistant strains arises due to the production of a broad spectrum of ?-lactamases using various bacterial spp. after continuous consumption and became very common [ 31 van Duin D, Paterson DL. Multidrug-resistant bacteria in the community: trends and lessons learned. [http://dx.doi.org/10.1016/j.idc.2016.02.004] [PMID: 27208764] ]. Antimicrobial resistance is an important public health concern at the global level. However, in India, recent hospital and community based reports showed an incensement of microbial resistance [ 32 Kumar SG, Adithan C, Harish BN, Sujatha S, Roy G, Malini A.

[http://dx.doi.org/10.4103/0976-9668.116970] [PMID: 24082718] ]. The reports showed varied resistance in different antibiotic resistance rates of various organisms along with various parts of India, as shown in Table 1 .

AMR in the world and emergence of newer Multi-Drug Resistant (MDR) and Extreme Drug Resistance (XDR) strains pose newer diagnostic and therapeutic challenges [ 33 Patil K, Bagade S, Bonde S, Sharma S, Saraogi G. Recent therapeutic approaches for the management of tuberculosis: Challenges and opportunities.

[http://dx.doi.org/10.1016/j.biopha.2018.01.115] [PMID: 29710471] ]. However, developed and developing countries are still striving to combat deep-rooted diseases such as tuberculosis, malaria and cholera pathogens, which are becoming with more drug resistant strains [ 34 John TJ, Dandona L, Sharma VP, Kakkar M. Continuing challenge of infectious diseases in India. [http://dx.doi.org/10.1016/S0140-6736(10)61265-2] [PMID: 21227500] ]. Several factors such as poverty, illiteracy, overcrowding and malnutrition further contribute to such kind of situation [ 35 Bajpai V. The challenges confronting public hospitals in India, their origins, and possible solutions.

Lower healthcare professional to patient ratios is also involved for such kind of concern. CASE STUDIES OF RESISTANCE DEVELOPMENT AND AFFECTING FACTORS.



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11.01.2015 - YagmurGozlum
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17.03.2015 - 21
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04.04.2015 - BaKiLi_QaQaS
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07.04.2015 - 665
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23.04.2015 - SEBINE
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