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Amoxicillin can also be used “off-label” to treat anthrax. Amoxicillin should only be used “off-label,” in other words, for purposes not usually specified, if specifically recommended by a healthcare provider. Amoxicillin can be taken orally as a dry tablet, a chewable tablet, a capsule, a suspension, or liquid preparation, or as drops for children. Amoxicillin is normally taken either twice a day, every 12 hours, or three times a day, every 8 hours, depending on the doctor’s instruction. It may be taken with or without food, and the liquid form can be mixed with other liquids such as baby formula, fruit juice, milk, and water. Liquids and drops should be shaken thoroughly before use to ensure that the medication is distributed evenly. Tablets and capsules should be taken with water, and chewable tablets should be fully chewed before swallowing.

It is important to follow the exact dosage and frequency as instructed by health care providers.

If a dose is missed, one should be taken as soon as possible unless it is nearly time for the next dose.

Never take a double dose to make up for a missed one.

Even if symptoms resolve, the patient must follow

the

treatment course to the end.

Discontinuing treatment before the end of the prescribed course increases the risk of bacteria developing a resistance to the antibiotic. Like many forms of medication, amoxicillin can have unwanted side effects. Some of these are more common, and some are more severe. It is most important for doctors to check whether the patient is allergic to penicillin because an anaphylactic reaction can be fatal.

Signs

and

symptoms of an allergic reaction include: chest tightness difficulty breathing rash or hives itchiness swelling of the face or throat. Anyone experiencing any of these symptoms while taking amoxicillin should seek urgent medical attention.

Between 1 and 10 percent of patients will experience an upset stomach, possibly with vomiting and diarrhea, due to Clostridium difficile (C. This is because the antibiotic changes the gut flora. Between 1 and 10 percent will develop candidiasis, a fungal or myotic infection.

Patients who are concerned about these side effects should contact their doctor.

Some people experience vaginal itching or a swollen, black tongue that feels “hairy.” Less common but more serious adverse effects include: severe skin rash or hives seizures yellowing of the eyes or skin or dark-colored or bloody urine pale skin unusual bleeding or bruising fatigue.

For more information and a full list of adverse effects, patients should check the patient information leaflet (PIL) that comes with the medication or speak to their healthcare provider. It is very important that a doctor is aware of what medication a patient is taking before prescribing amoxicillin. Amoxicillin works well with some forms of medication such as clarithromycin and lansoprazole, but with other drugs, there may be unwanted interactions.

Interaction can occur with: anticoagulant drugs such as warfarin treatments for gout, such as probenecid and allopurinol other antibacterials, such as chloramphenicol, klamoks amoxicillin clavulanic acid macrolides, sulfonamides, and tetracycline methotrexate, used in cancer therapy some muscle relaxants oral typhoid vaccine. increasing or

reducing

the effectiveness of other drugs increasing toxicity by reducing

the

body’s ability to excrete the drug after use. Amoxicillin can also affect the results of certain diagnostic tests, such as urine glucose tests.

Doctors and other health care providers must be fully informed of any

other

drugs, treatments or tests that a patient is being given before they prescribe amoxicillin.

They may need to change the dosage or take extra precautions.

Anyone who takes an overdose should call their local poison center at 1-800-222-1222.

Amoxicillin may reduce the effectiveness of birth control measures, such as patches, rings, or the birth control pill. A secondary prevention method such as condoms may be needed during the treatment course. Anyone who is using these methods of birth control should discuss their options with their physician or health care provider. Although amoxicillin can treat certain infections effectively, repeated use can reduce its effectiveness.

A 20-year study published in the BMJ in 2014 found that 1 in 10 of all antibiotic prescriptions failed to treat the infection.

This would appear to indicate a growing tendency toward antibiotic resistance, where overuse of antibiotics is reducing their effectiveness.

For this reason, doctors need to be sure that the patient’s condition is caused by a bacteria, and to

know

if a patient has previously used amoxicillin. Alcohol does not affect the antibiotic activity of amoxicillin, but patients should avoid drinking alcohol while an active infection is present.

This can support the body in effectively eradicating infection.



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