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Analogue of ampicillin, is a semisynthetic antibiotic with essentially the all patients who present agar (Biokar®) were prepared and sterilized according to the manufacturers’ instructions. Another drug and may not reflect the rates.

Used in clinical pharmacokinetic studies of AMO in humans mg-125 mg, oval cancer patients and making routine surgery a safer option e.g. And clarithromycin) – can be particularly useful for treating lung and chest difficulty.

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Oral Dental abscesses Adult: Initially, 3 g, repeat once after 8 hours. Oral Uncomplicated acute urinary tract infections Adult: Initially, 3 g, repeat once after 10-12 hours. Oral Prophylaxis of endocarditis Adult: 2 or 3 g as a single dose, 1 hour before dental procedure.

Oral Severe or recurrent respiratory tract infections Adult: 3 g bid. Renal impairment: Patients on haemodialysis should receive 250-500 mg every 24 hours and an additional dose during and after each dialysis session. CrCl (ml/min) Dosage Recommendation 10-30 250-500 mg every 12 hours. Oral Otitis media Child: 3-10 years: 750 mg bid for 2 days.

Renal impairment: Patients on haemodialysis should receive 250-500 mg every 24 hours and an additional dose during and after each dialysis session. CrCl (ml/min) Dosage Recommendation 10-30 250-500 mg every 12 hours. Oral H.pylori infection Adult: 0.75 or 1 g bid or 500 mg tid in combination with either metronidazole or clarithromycin and a bismuth compound or an antisecretory drug.

Renal impairment: Patients on haemodialysis should receive 250-500 mg every 24 hours and an additional dose during and after each dialysis session.

CrCl (ml/min) Dosage Recommendation 10-30 250-500 mg every 12 hours.

Intravenous Listerial meningitis Adult: 2 g every 4 hours for 10–14 days via IV infusion, to be used with other antibiotics. Renal impairment: Patients on haemodialysis should receive 250-500 mg every 24 hours and an additional dose during and after each dialysis session. CrCl (ml/min) Dosage Recommendation 10-30 250-500 mg every 12 hours. Parenteral Susceptible infections Adult: 500 mg every 8 hours via IM or slow IV injection.

Severe infections: May increase to 1 g every 6 hours via slow IV injection over 3-4 minutes or infuse over 30-60 minutes. Child: ?10 years: 50-100 mg/kg daily in divided doses.

Renal impairment: Patients on haemodialysis should receive 250-500 mg every 24 hours and an additional dose during and after each dialysis session.

CrCl (ml/min) Dosage Recommendation 10-30 250-500 mg every 12 hours. Category B: Either animal-reproduction studies have not demonstrated a foetal risk but

there

are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Study Details Tabular View No Results Posted Disclaimer How to Read a Study Record. Condition or disease Intervention/treatment Phase Periodontitis Procedure: SRP Other: Placebo Drug: MTZ+AMX Phase 4.

Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 58 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) Primary Purpose: Treatment Official Title: Metronidazole and Amoxicillin as Adjuncts to Scaling and Root Planing for the Treatment of Type 2 Diabetic Subjects With Periodontitis: a Randomized Placebo-controlled Clinical Trial Study Start Date : September 2011 Estimated Primary Completion Date : October 2014 Estimated Study Completion Date : October 2014. Choosing to participate in a study is an important personal decision.

Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study

research

staff using the contacts provided below.

For general information, Learn About Clinical Studies. Layout table for eligibility information Ages Eligible for Study: 35 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No. ? 35 years of age Diagnosis of type 2 DM for ? 5 years DM treatment with diet and insulin supplementation or oral hypoglycemic agents Glycated hemoglobin (HbA1c) levels ? 6.5% ? 11% At least 15 teeth More than 30% of the sites with probing depth (PD)

and

clinical attachment level (CAL) ? 4 mm Minimum of six teeth with at least one site with PD and CAL ? 5 mm and bleeding on probing (BoP) at baseline.

Pregnancy Lactation Current smoking Smoking within the past 5 years Scaling and root planing (SRP) in the previous 12 months Antimicrobial therapies during the previous 6 months Medical conditions requiring prophylactic antibiotic coverage Continuous use of mouthrinses containing antimicrobials in the preceding 3 months Systemic conditions (except DM) that could affect the progression of periodontitis (e.g. immunological disorders, osteoporosis) Long-term administration of anti-inflammatory Long-term administration of immunosuppressive medications Allergy to metronidazole and/or amoxicillin Presence of periapical pathology Use of orthodontic appliances Presence of extensive prosthetic rehabilitation Major complications of DM (i.e.

cardiovascular and peripheral vascular diseases [ulcers, gangrene and amputation], neuropathy and nephropathy) To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

This sheet talks about exposure to Amoxicillin and Clavulanate in a pregnancy and while breastfeeding. This information should not take the place of medical care and advice from your healthcare provider.

This combination medication is an antibiotic

used

to treat a variety of bacterial infections. It is a combination of amoxicillin, a penicillin-like antibiotic, and clavulanate, a drug that increases the effectiveness of amoxicillin.

Brand names include Amoclav®, Augmentin XR® and Clavamox®.

Studies have not been done to

see

if amox/clav could make it harder for a woman to

become

pregnant.

If you were prescribed amox/clav by your healthcare provider, talk with them before making any changes in how you take this medication.

It is important to consider the benefits of treating infections during pregnancy.

Does taking amox/clav increase the chance of miscarriage?

When taken in the recommended doses, amox/clav is unlikely to increase the chance for miscarriage. Does taking amox/clav in the first trimester increase the chance of birth defects?

In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. Most studies have not found an increased chance for birth defects when amox/clav is taken during the first trimester; however, there are very few studies available. There are more studies looking at the use of amoxicillin alone during pregnancy.

A few studies have shown an higher chance of cleft lip (opening in the lip) with or without cleft palate (opening in the roof of the mouth) when

amoxicillin

is taken during the first trimester.

However there are other studies that have not found a higher chance for cleft lip with or without cleft palate. Based on the current information, the overall chance of a cleft in lip and/or palate is considered to be low if a woman is taking amox/clav in a pregnacy. Could taking amox/clav in the second or third trimester cause other pregnancy complications?

There is limited information regarding the use of amox/clav during the second trimester, but studies so far do not report an increased chance for pregnancy problems when used in this time period.



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