Sildenafil professional 100mg

Due to the lack of data on the effect of sildenafil indicated for the treatment of pulmonary arterial hypertension (PAH) in pregnant women, sildenafil is not recommended for women of childbearing potential unless also using appropriate contraceptive measures 11,14,15,9 . The safety and efficacy of sildenafil indicated for treating PAH in a woman during labor and delivery have not been studied 11,14,15,9 . Caution should ultimately be exercised when sildenafil is administered to nursing women as it is not known if sildenafil or its metabolites are excreted in human breast milk 11,14,15,9 .

The safety and efficacy of sildenafil for the treatment of PAH in children below 1 year of age has not been established as no data is available 15 .

Clinical experience with the elderly population in the use of sildenafil for the treatment of PAH has been varied. Some reports suggest that there are no identified differences in responses between elderly and younger patients 11 while others have documented that clinical efficacy as measured by 6-minute walk distance could be less in elderly patients 9 . In general, dose selection for an elderly patient should be cautious, reflecting the cipla viagra 100mg price greater frequency of decreased sildenafil professional 100mg hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy 11 .

Conversely, when sildenafil was used to treat erectile dysfunction in healthy elderly volunteers (65 years or over), a reduced clearance of sildenafil was observed 12,8 .

This reduction resulted in about 90% higher plasma concentrations of sildenafil and the active N-desmethyl metabolite compared to those seen in healthy younger volunteers (18-45 years) 12,8 .

Due to age-differences in plasma protein binding, the corresponding increase in free sildenafil plasma concentration was approximately 40% 12,8 . Sildenafil was not carcinogenic when administered to rats for 24 months at a dose resulting in total systemic drug exposure (AUCs) for unbound sildenafil and its major metabolite of 29- and 42- times, for male and female rats, respectively, the exposures observed in human males given the Maximum Recommended Human Dose (MRHD) of 100 mg 11,12,13,14,15,16,8,9 .

Sildenafil was not carcinogenic when administered to mice for 18-21 months at dosages up to the Maximum Tolerated Dose (MTD) of 10 mg/kg/day, approximately 0.6 times the MRHD on a mg/m2 basis 11,12,13,14,15,16,8,9 . Sildenafil was negative in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity 11,12,13,14,15,16,8,9 .

There was no impairment of fertility in rats sildenafil professional 100mg given sildenafil up to 60 mg/kg/day for 36 days to females and 102 days to males, a dose producing an AUC value of more than 25 sildenafil professional 100mg times the human male AUC 11,12,13,14,15,16,8,9 .

Affected organisms Humans and other mammals Pathways Not Available Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" href="javascript:void(0);"> sildenafil (oral) Pronunciation: sil DEN a fil. 20 mg, round, white, imprinted with RVT 20, pfizer.

25 mg, diamond, blue, imprinted with Pfizer, VGR 25. 50 mg, diamond, blue, imprinted with Pfizer, VGR 50. 100 mg, diamond, blue, imprinted with Pfizer, VGR 100.

100 mg, diamond, blue, imprinted with Pfizer, VGR 100. 100 mg, diamond, blue, imprinted with Pfizer, VGR 100. 25 mg, diamond, blue, imprinted with Pfizer, VGR 25.

50 mg, diamond, blue, imprinted with Pfizer, VGR 50. What is the most important information I should know about oral sildenafil?

Some medicines can cause unwanted or dangerous effects when used with sildenafil.

Tell your doctor about all your current medicines, especially riociguat (Adempas). Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers".

Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours.

A prolonged erection (priapism) can damage the penis.

Stop using sildenafil and get emergency medical help if you have sudden vision loss.

Sildenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men.

Another brand of sildenafil is Revatio , which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Do not take Viagra while also taking Revatio, unless your doctor tells you to.

Sildenafil may also be used for purposes not listed in this medication guide. What should I discuss with my healthcare sildenafil professional 100mg provider before taking oral sildenafil?

You should not use sildenafil if you are allergic to it, or: if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).

Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.