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Stendra is the newest drug on the market, and no generic version is available for sale yet. The 100-mg and 200-mg doses can be taken as shortly as 15 minutes before sexual activity. As a second-generation medication, Stendra also seems to have milder side effects than Viagra and the other PDE5 inhibitors that came before it.

Side effects commonly caused by Viagra — but not Stendra — include dizziness, vision changes, nausea, and muscle aches.

The only common side effect caused by Stendra but not Viagra is a sore throat. Each drug comes with the risk of drug interactions. Since PDE5 inhibitors work on the body in similar ways, Viagra, Cialis, Levitra, and Stendra lead to similar interactions. All four of these drugs interact with: nitrates, such as isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) certain blood pressure drugs, such as calcium channel blockers alpha blockers, which can treat high blood pressure or an enlarged prostate certain pulmonary hypertension drugs, such as riociguat (Adempas) protease inhibitors, a class of HIV drugs antifungal drugs, such as ketoconazole and itraconazole (Onmel, Sporanox) antibacterial drugs, such as clarithromycin (Biaxin) Drinking excessive amounts of alcohol while on any PDE5 inhibitor should be avoided, and you shouldn’t combine different ED drugs.

Cialis may also be less effective if used alongside antiseizure medications such as carbamazepine (Tegretol) and phenobarbital.

For specifics on which medications are safe for you to use, it’s best to consult your doctor or pharmacist.

In some cases, using these medications may mean you need to completely avoid PDE5 inhibitors. In other cases, adjusting your dosage of the medication can reduce the possibility of drug interactions while using PDE5 inhibitors. If you have ED, talk to your doctor about Viagra, Cialis, Levitra, and Stendra.

Tell your doctor if you take other over-the-counter or prescription drugs or supplements. Be sure to mention all other health conditions you have.

When used correctly, each of these drugs has been shown to help men with ED. If you have questions or concerns, talk with your doctor. All of them lead to good results, but it may take a little time and patience to get it right.

If one drug doesn’t work or produces unpleasant side effects, you can try another drug.

It may also take some trial and error to find the dosage that works best for you. If you’re not sure that drug treatment is right for you, you can also give natural ED treatments a try. Cialis (tadalafil) and Viagra (sildenafil) are phosphodiesterase-5 (PDE5) inhibitors used for treating impotence (erectile dysfunction, or ED). Common side effects of Cialis and Viagra that are similar include flushing (redness or warmth of the face, neck, or chest), headaches, stomach pain or upset, flu-like symptoms (such as stuffy nose, sneezing, or sore throat), memory problems, muscle or back pain, blurred vision and changes in color vision (such as an inability to differentiate between the colors green and blue), dizziness, diarrhea, nausea, low blood pressure, abnormal ejaculation, and prolonged erections (priapism), loss of hearing, and ringing in the ears. One difference between the drugs is how long they stay in your system. Cialis provides penile hardness (the ability to obtain an erection) over a longer period than Viagra because it lasts up to 18 hours, while Viagra only lasts for about 4 to 6. Cialis (tadalafil) and Viagra (sildenafil) are oral drugs that are used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH).

They are in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes vardenafil (Levitra, Staxyn ODT), and avanafil (Stendra). Penile erection is caused by the engorgement of the penis with blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis.

Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Cialis and Viagra inhibit an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Cialis and Viagra prevent the destruction of reddit online cialis cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis. If you are taking Cialis and you have nausea, chest pain or dizziness during sex, seek medical help immediately as you may have a life-threatening condition.

The most common side effects of tadalafil are: facial flushing (reddening), headaches, stomach upset, diarrhea, flu-like symptoms, and nausea.

Tadalafil also may cause: low blood pressure, blurred vision, changes in color vision, and abnormal ejaculation.

Priapism, or an erection that lasts more than four hours that can damage the penis. If you are taking Viagra and you have nausea, chest pain or dizziness during sex, seek medical help immediately as you may have a life-threatening condition.

Approximately 15% of persons taking Viagra experience side effects.

The most common side effects are: facial flushing (1 in 10), headaches (1 in 6), stomach pain, nasal congestion, nausea, dizziness, rash, urinary tract infections (UTIs) diarrhea, and an inability to differentiate between the colors green and blue.

Priapism, or an erection that lasts more than four hours that can damage the penis.

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Depending on the adequacy of the response or side effects, the dose may be increased to 20 mg or decreased to 5 mg a day. Individuals who are taking medications that increase the blood levels of tadalafil should not exceed a total dose of 10 mg in 72 hours (See drug interactions). For once daily use without regard to sexual activity, the recommended dose is 2.5 to 5 mg daily. Tadalafil should not be taken more than once daily. The recommended dose for BPH, or BPH and ED is 5 mg daily taken about the same time each day.

Tadalafil may be taken with or without food since food does not affect its absorption from the intestine. The dose of tadalafil may require adjustment for patients with reduced kidney or liver function. The usual recommended dose is 25 to 100 mg 1 hour before sexual activity.

The elderly (over 65 years of age) should start at 25 mg before sexual activity.

Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. When sildenafil is taken with a high fat meal, the rate of absorption is reduced, with reddit online cialis an average delay in the time to maximal concentration of 1 hour.

The breakdown and elimination of tadalafil from the body may be decreased by erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir).

Therefore, these drugs may increase the levels of tadalafil in the blood. If these drugs are being used at the same time as tadalafil, the dose of tadalafil should be reduced to 10 mg every 72 hours when used as needed or 2.5 mg when used daily in order to avoid side effects from high levels of tadalafil. Rifampin, carbamazepine (Tegretol, Tegretol XR, Equerto, Carbatrol), phenytoin (Dilantin, Dilantin-125), and phenobarbital may decrease blood levels of tadalafil, possibly reducing the effect of tadalafil. Tadalafil exaggerates the increases in heart rate and lowering of blood pressure caused by nitrates, for example, nitroglycerin, isosorbide dinitrate (Isordil), isosorbide mononitrate (Imdur, Ismo, Monoket), nitroglycerin (Nitro-Dur, Transderm-Nitro) that are used primarily for treating heart pain (angina).

In patients who take nitrates for angina, tadalafil could cause heart pain or possibly even a heart attack by exaggerating the increase in heart rate and the lowering of blood pressure.

Therefore, tadalafil should not be used with nitrates.

Tadalafil also exaggerates the blood pressure lowering effects of some alpha-blocking drugs for example, terazosin (Hytrin) that primarily are used for treating high blood pressure or enlargement of the prostate (BPH). Individuals who take these alpha-blockers should be on a stable dose of the alpha-blocker before tadalafil is started.

In such situations, tadalafil should be started at the lowest dose.

If the patient is already taking tadalafil, the alpha-blocker should be started at the lowest dose.

Combining tadalafil with alpha-blockers for treatment of BPH is not recommended. Therefore, combining tadalafil with alcohol may cause excessive drops in blood pressure and cause dizziness, headaches, and increased heart rate.

PDE5 inhibitors may affect platelet function and therefore prolong bleeding. Tadalafil should be used cautiously in patients with bleeding disorders or active ulcers.

Tadalafil should not be combined with Adcirca (another form of tadalafil) or other PDE5 inhibitors, for example, vardenafil (Levitra) or sildenafil (Viagra, Revatio). Viagra increases the effects of the blood pressure lowering medications.

It also increases the blood pressure lowering effects of nitrates, for example, isosorbide dinitrate (Isordil), isosorbide mononitrate (Imdur, Ismo, Monoket), nitroglycerin (Nitro-Dur, Transderm-Nitro) that are used primarily for treating angina.

Patients taking nitrates should not receive Viagra. Patients should not combine Viagra with other PDE5 inhibitors (for example, vardenafil [Levitra], tadalafil [Cialis]). Cimetidine (Tagamet), erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), atazanavir (Reyataz), and mibefradil (Posicor) can cause marked increases in the amount of Viagra in the body. Patients taking these medications should be observed carefully if sildenafil is used. It is expected that rifampin will decrease blood levels of Viagra and probably reduce its effectiveness. Are Cialis and Viagra safe to use while pregnant and breastfeeding?

Tadalafil is not approved for women and has not been evaluated in women who are breastfeeding. Although extensive testing in animals has demonstrated no negative effects on the fetus, Viagra has not been studied in pregnant women. There is no effect on sperm count or motility of sperm in men. It is not known whether sildenafil is excreted into breast milk.

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By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time. Cialis (tadalafil) and Viagra (sildenafil) are oral drugs that are used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH). They are in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes vardenafil (Levitra, Staxyn ODT), and avanafil (Stendra). Learn about erectile dysfunction causes and treatments such as drugs. Enlarged Prostate (BPH) Symptoms, Diagnosis, Treatment.

Benign Prostatic Hyperplasia (BPH) is a condition cause by an enlarged prostate. Here we explore how stress, lack of sleep, weight gain, depression and low T can. Learn sex tips for men that lead to more sexual pleasure such as better communication, focusing on pleasurable sensations.

Learn how to overcome common health conditions affecting those over 50 such as.

Benign Prostatic Hyperplasia (Enlarged Prostate) Quiz. Take the Enlarge Prostate Quiz and challenge your knowledge of prostate problems.

Erectile Dysfunction (Impotence) Quiz: Causes & Treatment. Did you know that certain medical condition may be responsible for ED? Some causes of impotence are medically treatable and.

Male sexual dysfunction can be caused by physical or psychological problems.

Common sexual problems in men include erectile dysfunction (impotence or ED), premature ejaculation, and loss of libido. Treatment for sexual dysfunction in men may involve medication, hormone therapy, psychological therapy, and the use of mechanical aids.

Enlarged Prostate (BPH, Benign Prostatic Hyperplasia) Benign prostatic hyperplasia (BPH or enlarged prostate) is very common in men over 50 years of age.

Half of all men over the age of 50 develop symptoms of BPH, but few need medical treatment.

This noncancerous enlargement of the prostate can impede urine flow, slow the flow of urine, create the urge to urinate frequently and cause other symptoms like complete blockage of urine and urinary tract infections.

More serious symptoms are urinary tract infections (UTIs) and complete blockage of the urethra, which may be a medical emergency. Not all men with the condition need treatment, and usually is closely monitored if no symptoms are present. Treatment measures usually are reserved for men with significant symptoms, and can include medications, surgery, microwave therapy, and laser procedures.

Men can prevent prostate problems by having regular medical checkups that include a prostate exam.

BPH (Enlarged Prostate) Differences and Similarities.

Prostatitis and BPH (benign prostatic hyperplasia, enlarged prostate gland) are both conditions of the prostate gland. There are four types of prostatitis that can be caused by infections (usually bacterial) or other health conditions or problems, acute bacterial prostatitis (type I), chronic bacterial prostatitis (type II), chronic prostatitis and chronic pelvic pain syndrome (type III), and asymptomatic inflammatory prostatitis (type IV). BPH is inflammation of the prostate gland, and most men have the condition by age 50. Doctor's don't know what causes this inflammation, but they theorize that it may be related to hormones. Both of these conditions can cause similar symptoms like low back pain, pain during urination, or difficulty or the inability to urinate. However, prostatitis has many more symptoms and signs than BPH, and they based on the type of prostatitis. Examples include low back pain and/or abdominal pain, painful urination, fever, chills, feeling tired, recurrent urinary tract infections (UTIs), painful urination intermittently, intermittent obstruction urinary tract symptoms (frequent, painful, or incomplete urination), pelvic pain and/or discomfort, pain with ejaculation, and erectile dysfunction (ED).

If you think you have either of these conditions contact your doctor or other health care professional.

Bacterial prostatitis can be cured with antibiotics; however, there is no cure for BPH.

Erectile Dysfunction (ED, Impotence) Erectile dysfunction (ED, impotence) is the failure to achieve or maintain an erection.

There are many potential underlying causes of erectile dysfunction, including stress and emotional problems, brain dysfunction, problems with blood supply to the penis, and structural problems with the penis. Erectile dysfunction is diagnosed by taking the patient's history and physical exam.

Blood tests measuring kidney function and blood sugar, cholesterol, hormone, and prostate-specific antigen (PSA) levels may be ordered.