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Improved erections were reported in: 57% of men who took Viagra 10% of men who took a placebo. One study only involved men with ED that resulted from a spinal cord injury. Improved erections were reported in: 83% of men who took Viagra 12% of men who took a placebo. Also, using information from multiple studies, researchers looked at how well Viagra worked in men with ED that developed after they’d had surgery to remove their prostate gland. Improved erections were reported in: 43% of men who took Viagra 15% of men who took a placebo. In addition, men whose ED had psychological causes were specifically looked at as part of one study. Improved erections were reported in: 84% of men who took Viagra 26% of men who took a placebo. In addition to the use described above, Viagra may be used off-label.

Off-label drug use is when a drug that’s approved for one condition is given for a different condition that’s not approved. Below is an example of an off-label use for Viagra. Viagra isn’t approved to treat Raynaud’s disease, but sometimes it’s used off-label for this condition.

With Raynaud’s disease, the blood vessels in your hands and feet spasm and temporarily become narrowed.

These narrowed blood vessels restrict blood supply to your fingers or toes. This can cause your fingers and toes to look white and feel cold, painful, or numb.

Episodes of spasm can be triggered by cold temperatures or emotional stress. Viagra works to treat Raynaud’s disease by relaxing and widening certain blood vessels in your body. One review of studies found that PDE5 inhibitors, including Viagra, can improve Raynaud’s disease.

(PDE5 inhibitors describes a certain class of drugs.

Medications in the same class of drugs work in a similar way inside your body.) In fact, in the studies, these drugs reduced the number of Raynaud’s disease episodes people had. And the drugs also decreased how long the episodes lasted.

If you have questions about using Viagra

for

Raynaud’s disease, talk with your doctor.

Viagra is only approved for use in

adult

males with ED.

It hasn’t been studied in people younger than 18 years of age. Viagra is approved to treat erectile dysfunction (ED) in men. But you may have questions about whether Viagra can be used in women.

Or you may be wondering if there’s a drug similar to Viagra that can help women with sexual dysfunction.

And there isn’t enough evidence to mazzogran 100 mg price show that Viagra works for treating sexual problems in women. One review of studies showed that current research has conflicting results on how Viagra affects women.

For example, in women with female sexual arousal disorder,

the

review showed the following findings: In one study, some women who’d gone through menopause were given Viagra.

These women had improved arousal, vaginal lubrication, and orgasm when they took the drug.

In another study, both women who’d gone through menopause and those who hadn’t were given Viagra.

These women reported no significant positive effects from taking the drug.

In men, Viagra improves blood flow to their penis by blocking the action of a chemical called PDE5. This chemical is also found in the vagina and the clitoris of women.

So in theory, if a woman takes Viagra, it could increase blood flow to her genitals.

But in reality, there’s less PDE5 in a female’s genitals than there is in a male’s penis. This could explain why Viagra has less of a physical effect in women than it does in men.

And keep in mind that sexual problems in women often have a lot to do with reduced sexual desire and arousal.

While Viagra isn’t approved for use in women, a drug called Addyi is approved for use in certain women. Some people refer to Addyi as “female Viagra.” However, Addyi doesn’t work like Viagra does.

Below, we describe the condition Addyi is approved to treat and how the drug works. If you have questions about using Addyi, talk with your doctor.

Addyi is a brand-name prescription drug that’s approved to treat hypoactive sexual desire disorder (HDSS).

It’s prescribed for women who haven’t yet gone through menopause. It’s

not

known for sure how Addyi works to treat HDSS.

With HDSS, you have very low sexual desire that’s troublesome for you. The condition can have various physical or psychological causes.

Unlike

Viagra, which improves blood flow to male genitals, Addyi doesn’t work by improving blood flow to female genitals. Instead, Addyi affects the activity of certain neurotransmitters that are involved in sexual desire and arousal. (Neurotransmitters are chemicals found in your brain.) The neurotransmitters affected by Addyi include dopamine, noradrenaline, and serotonin. But it’s not known for sure how the drug’s action affects sexual function. For some women with HDSS, Addyi can improve sexual desire and increase the number of sexually satisfying events.

But the drug hasn’t been found to be very effective.

For example, in clinical studies, treatment with Addyi was compared with that of a placebo (no active drug). The number of women whose HDSS was “much improved” or “very much improved” was only about 10% higher in women who took Addyi compared with women who took the placebo.

And keep in mind that it can take up to 8 weeks for Addyi to start working to treat HDSS. When you get Viagra from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically 1 year from the date they dispensed the medication.

The expiration date helps guarantee that the medication is effective during this time. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications.

If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. How long a medication remains good (also called shelf-life) can depend on many factors. These factors include how and where you store the medication.

Viagra tablets should be stored at room temperature between 68 o F and 77°F (20 o C and 25°C).

It should be kept in a tightly sealed container away from

light

. Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms. If you no longer need to take Viagra and have leftover medication, it’s important to dispose of it safely. This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment.

This article provides several useful tips on medication disposal. You can also ask your pharmacist for information on how to dispose of your medication. Using more than the recommended dosage of Viagra can lead to serious side effects.

Do not use more Viagra than your doctor recommends. What to do if you think you’ve taken too much Viagra.

If you think you’ve taken too much of this drug, call your doctor. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away. Before taking Viagra, talk with your doctor about your health history. Viagra may not be right for you if you have certain medical conditions or other factors affecting your health. These include: History of allergic reaction to Viagra mazzogran 100 mg price or sildenafil. Don’t take Viagra if you’ve ever had an allergic reaction to Viagra or sildenafil (the active drug in Viagra).

If you’re not sure of your medication allergies, talk with your doctor. If you have a heart problem, or you’ve had a heart problem or stroke in the past, talk with your doctor about whether Viagra is safe for you. Heart problems include conditions such as angina (a type of chest pain), heart attack, heart failure, and aortic stenosis (narrowing of the main artery that leaves your heart). Heart problems also include irregular heartbeat patterns, such as atrial fibrillation (A-fib).

Taking Viagra and having sexual activity may not be recommended if your doctor thinks that doing so will put too much strain on your heart.

If you have a heart problem and you take Viagra, stop sexual activity if you get any chest pain, dizziness, or nausea.

And don’t take nitrate medications to treat chest pain while you’re using Viagra. If you have any heart-related symptoms, call 911 if the symptoms feel life threatening or if you think you’re having a medical emergency. And be sure to see your doctor before taking Viagra again.

If you’re taking medication to treat high blood pressure, taking Viagra could cause your blood pressure to drop even further.

In some cases, this could make you feel dizzy or lightheaded, or cause you to faint.

And if you have high blood pressure that’s not controlled (measuring higher than 170/110 mmHg), your heart may not be healthy enough for sex. If you have high blood pressure, talk with your doctor about whether Viagra is right for you.

If you’re able to take Viagra,

your

doctor will usually prescribe a dosage for you that’s lower than the typical dosage. If you already have low blood pressure, taking Viagra can make it drop even further.

This could make you feel dizzy or lightheaded, or cause you to faint.

If your blood pressure is below 90/50 mmHg, talk with your doctor about whether Viagra is right for you.

If you are able to take Viagra, your doctor will usually prescribe a dosage for you that’s lower than the typical dosage.

If you have problems with your penis, such as bending, scarring, or Peyronie’s disease, it might not be safe for you to take

Viagra

. (With Peyronie’s disease, you have an abnormal curvature of your penis.) Rarely, Viagra may cause priapism (a long-lasting and sometimes painful erection).

If you have a physical problem affecting your penis, getting priapism with Viagra could cause further damage to your penis.

Talk with your doctor

about

whether Viagra is right for you. If you have a blood cell problem, such as sickle cell anemia, multiple myeloma, or leukemia, Viagra may not be safe for you. This is because having these conditions could increase your risk of priapism (a long-lasting and sometimes painful erection) with Viagra. Talk with your doctor about whether Viagra is right for you.

Non-arteritic anterior

ischemic

optic neuropathy (NAION).

NAION is an eye condition that causes damage to your optic nerve.

This damage causes a sudden decrease or loss of vision in one or both eyes.

If you’ve already had this eye condition in the past, you could have a higher risk of developing it with Viagra. Talk with your doctor about whether Viagra is right for you. This condition, which affects your eye, is passed down in families.

Viagra hasn’t been studied in people with hereditary retinitis pigmentosa. Talk with your doctor about any eye problems you may have.

If you have certain kidney problems and your kidneys don’t work well,Viagra can build up in your body.

This can increase your risk of side effects from the drug. If you have severe kidney problems, your doctor will prescribe a dosage of Viagra for you that’s lower than the typical dosage.

If you have certain liver problems and your liver doesn’t work well, Viagra can build up in your body.

This can increase your risk of side effects from the drug. If you have liver problems, your doctor will prescribe a dosage of Viagra for you that’s lower than the typical dosage.

There have been a few reports of bleeding in people who’ve taken Viagra since this drug was approved and released onto the market. However, there’s no evidence that Viagra caused these problems. It’s not known if Viagra is safe for people with a bleeding problem.

If you have any bleeding problems, talk with your doctor about whether Viagra is right for you. It’s not known whether Viagra is

safe

for

people

who have a peptic ulcer. If you have or have had an ulcer in the past, talk with your doctor about whether Viagra is suitable for you.

For more information, please see the “Viagra and pregnancy” section below. For more information, please see the “Viagra and breastfeeding” section below. Note: For more information about the potential negative effects of Viagra, see the “Viagra side effects” section above. As with all medications, the cost of Viagra can vary.

To find current prices for Viagra in your area, check out GoodRx.com. The cost you find on GoodRx.com is what you may pay without insurance.

The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. Your insurance plan may require you to get prior authorization before approving coverage for Viagra. This means that your doctor and insurance company will

need

to communicate about your prescription before the insurance company will cover the drug.

The insurance company will review the request and let you and your doctor know if your plan will cover Viagra.

If you’re not sure if you’ll need to get prior authorization for Viagra, contact your insurance company.

If you need financial support to pay for Viagra, or if you need help understanding your insurance coverage, help is available.

Pfizer, the manufacturer of Viagra, offers a program that can help lower the cost of Viagra. For more information and to find out if you’re eligible for support, call 855-842-4722 or visit the program website.

Viagra is available in generic form called sildenafil.

A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug. And generics tend to cost less than brand-name drugs.

To find out how the cost of sildenafil compares to the sildenafil 100mg paypal cost of Viagra, visit GoodRx.com.

Again, the cost you find on GoodRx.com is what you may pay without insurance. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use.

If your doctor has prescribed Viagra and you’re interested in using sildenafil instead, talk with your doctor. They may have a preference for one version or the other.

You’ll also need to check your insurance plan, as it may only cover one or the other.

It’s not known whether this drug is safe to take during pregnancy.

In animal studies, Viagra didn’t cause fetal harm when given to pregnant females. But animal studies don’t always predict what will happen in humans.

If you have questions about the safety of Viagra use during pregnancy, talk with your doctor.

It’s

not

known if Viagra is safe to take during pregnancy.

(But keep in mind that the drug isn’t approved for use in women.) If you’re sexually active and you or your partner can become pregnant, talk with your doctor about whether you’ll need to use birth control while you’re

taking

Viagra.

And it hasn’t been studied in women who are breastfeeding.

Viagra may pass into breast milk, but it’s not known if this could affect a nursing child.

If you have questions about the safety of using Viagra while breastfeeding, talk with your doctor. The following information is provided for clinicians and other healthcare professionals. Viagra is approved to treat erectile dysfunction (ED) in males ages 18 years and older.

It should be taken between 30 minutes and 4 hours before planned sexual activity.

Viagra contains sildenafil citrate, an inhibitor of phosphodiesterase type 5 (PDE5).

Viagra enhances the action of cyclic GMP, which is released in the penis in response to sexual stimulation.

Cyclic GMP dilates smooth muscle in the penile tissue. It also increases blood to flow into the corpus cavernosum, causing an erection. Viagra blocks PDE5 from breaking down cyclic GMP, thereby improving the ability to achieve and maintain an erection in response to sexual stimulation.

Sildenafil has an average bioavailability of 41% (ranges from 25% to 63%) after oral administration of Viagra tablets. When taken on an empty stomach, vigora tablet price 50 mg the time to reach peak plasma concentration (Tmax) is approximately 30 to 120 minutes.

Taking Viagra with a high-fat meal delays Tmax by about 60 minutes. It also reduces the maximum plasma concentration (Cmax) by an average of 29%. Sildenafil is primarily metabolized by hepatic CYP3A4, to a metabolite with similar activity to sildenafil. Sildenafil and its active metabolite have a terminal half-life of approximately 4 hours.

Approximately 80% of the dose is excreted in feces, and approximately 13% is excreted in urine.

Reduced clearance of sildenafil is seen in people ages 65 years and over, and in those with hepatic impairment or severe renal impairment.

Viagra is contraindicated in people with a known allergy to sildenafil, or any of the inactive ingredients in Viagra. Viagra is also contraindicated for use in combination with: nitrate drugs in any form, such as: nitroglycerin (Nitromist, Nitro-Dur, Nitrolingual Pumpspray, Gonitro, others) isosorbide mononitrate (Monoket) guanylate cyclase stimulators, such as riociguat (Adempas) Storage.

Store Viagra at room temperature between 68 o F and 77°F (20 o C and 25°C).

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your

doctor

or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.

The absence of

warnings

or other information for a given

drug

does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Braz J Med Biol Res, September 2005, Volume 38(9) 1303-1311 (Review) Effect of sildenafil citrate on the cardiovascular system. Cardiac Electrophysiology Unit, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Sildenafil citrate is a drug commonly used to manage erectile dysfunction.

It is designated chemically as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1 H -pyrazolo[4,3- d ]pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate (C 22 H 30 N 6 O 4 S). It is a highly selective inhibitor of cyclic guanine monophosphate-specific phosphodiesterase type 5.

In late March through mid-November 1998, the US Food and Drug Administration (FDA) published a report on 130 confirmed deaths among men (mean age, 64 years) who received prescriptions for sildenafil citrate, a period during which >6 million outpatient prescriptions (representing about 50 million tablets) were dispensed.

The US FDA recently reported that significant cardiovascular events, including sudden cardiac death, have occurred in men with erectile dysfunction who were taking sildenafil citrate. These reports have raised concerns that sildenafil citrate may increase the risk of cardiovascular events, particularly fatal arrhythmias, in patients with cardiovascular disease. In the past few years, the cardiac electrophysiological effects of sildenafil citrate have been investigated extensively in both animal and clinical studies.



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